The Bulls missed the double bonus point by one run but still pocketed a single bonus point with their 160-run victory to take them to the top of the table, one point ahead of NSW.
Queensland take on the Blues later this week at North Sydney Oval in a day/night match for their final regular season game which will determine if they host the one-day Final.
The Bulls today strode to a commanding 6-321 after South Australia won the toss and sent the home side into bat.
Openers Sam Heazlett, who produced a spirited run-a-ball 65, and captain Usman Khawaja (50) put on an opening stand of 118 from 19.4 overs, comfortably keeping the run rate up well above 5.5 an over.
Their dismissals slowed the momentum slightly as the Redbacks rallied off the back of some committed fielding before Marnus Labuschagne and Matt Renshaw got into a run-scoring groove of their own.
Both batsman targeted the short boundaries square of the wicket to pump the scoring rate back up as the Redbacks found themselves staring at a total well in excess of 300.
The Bulls run blitz was stymied slightly as the innings neared its end, with Labuschagne dismissed for 82 from 80 balls and Renshaw run out for 56 from 60 balls as the duo attempted to lift the scoring in the final 10 overs.
A hard-hitting 28 from Jack Wildermuth and a creative 19 not out from Jimmy Peirson, including two sixes in the final over, helped the Bulls secure a very competitive total, which was quickly backed up by a concerted bowling effort.
South Australia started firmly, but the Bulls attack withstood the initial blitz to quickly gain the ascendency.
In-form pacemen Billy Stanlake and Xavier Bartlett, the experienced Michael Neser and the equally impressive Matt Kuhnemann controlled the middle overs and collected wickets on a regular basis as South Australia was dismissed for 161, one run past the mark that would have earned a double bonus point.
Kuhnemann finished with a career best 4-37 while Neser (2-25), Bartlett (2-28) and Stanlake (1-26) reaped the rewards. The part-time off-spin of Renshaw was also effective with the big wicket of Alex Carey falling to him.