Just as they did in the semi-final and last round of the Cam Battersby Cup competition, University produced an assertive batting display to occupy the crease at Allan Border Field for the first two days of the four-day final played over two weekends.
The Blues batsmen hit three centuries in their first innings total of 526 to take a firm grasp on the title.
Rising left-hander Jack Clayton led the way with 119 as he combined with the prolific Ben Davis (53) and Dom Michael (48) to take his team to 3-251.
Valley hopes rose briefly, with a flurry of middle order wickets putting them back into contention as Uni wobbled at 6-267.
But then allrounder Jack Carty and wicket-keeper Mitchell Fry took the advantage away as the duo put on a compelling stand of 214 for the seventh wicket.
Carty hit 112 off 245 balls while Fry was 121 from 205 balls, including 17 fours and three sixes.
Valley attack stuck gamely to their task, although will rue not having the chance to bat first with Queensland Bulls paceman Mark Steketee and Luke Feldman eligible for the second weekend of the Final.
Captain Andrew Gode claimed 4-104 from a marathon 42 overs while young paceman Donal Whyte took 3-72 from 30 overs. Valley used eight bowlers as they delivered 184.1 overs.